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Our Pipeline

Pipeline

Our Programs

Reactive Oxygen Species (ROS), the fundamental cause of more than 90% of chronic diseases, is an incomplete oxygen molecule that occurs during the metabolic process of our body and attacks human cells when more than an appropriate amount accumulates in the body. Humans are born with Superoxide Disutase (SOD), an antioxidant enzyme that can defend against ROS, but aging progresses and its amount and activity continue to decrease.

Genofocus is developing high-purity SOD antioxidants produced using microbial improvement and secretion expression technologies as therapeutic materials. Regarding SOD, 4 domestic patents and 1 US patent registration were successful. It is Korea's first SOD that succeeded in obtaining a strain patent, and is developing a new drug that removes ROS, the fundamental cause of chronic diseases, with a continuous antioxidant effect.

SOD-based pharmaceutical candidate substance.

GF-101 : Wild Type

  • Health functional food ingredients.
    • The clinical efficacy of researchers.
      Validation and exploration of new indications.

GF-103 : Mutant

  • High purity protein medicine.
    • IBD and AMD treatments.
      Global clinical trials.

GF-203 : Spore

  • Effective microbial medicine.
  • SOD and treatment techniques are different. Effective substance production in the intestines.
    • Maximize the effectiveness of treatment.

GF-303 : EV

  • An extracellular vesicle
    equipped with SOD.(Extracellular Vesicle)
  • Absorption in the body.
    • Developing it as a respiratory
      treatment.

Novel microbiome-enzyme drug candidate.

Safety, CoGs, Efficacy 인체입증, Delivery, Combination Safety, CoGs, Efficacy 인체입증, Delivery, Combination
아이콘
Safety
Pharmaceutical/Food Microorganisms (GRAS) Derived
Securing safety as a drug candidate
아이콘
CoGs
Enzyme/microbial new drug production
plant GFSecuring price competitiveness
through maintenance
아이콘
Efficacy
Researchers can pre-verify the
effects in the human body
through clinical trials, discover
biomarker lines for patient selection
아이콘
Delivery
Spore delivery
→ stomach acid, bile acid,
protease resistance
Maximizing probiotic properties
아이콘
Combination
Contribute to enhancing the leadership of
existing drugs by focusing on enzymes
with mechanisms that create synergistic effects
with existing drugs